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Comparative Effectiveness Research and Evidence Based Medicine

Offered in collaboration with  UCI School of Medicine


In order to develop better outcomes while containing costs, physicians, nurses and other health care professionals need evidence of the effectiveness of various treatment regimens and related health care decisions. Comparative Effectiveness Research and Evidence Based Medicine is a rapidly growing field whose objective is to assess how various medical interventions result in improved health care outcomes. This work also provides a framework for healthcare professionals that yields more efficient medical decisions, reduces costs, and guides long term policy.

Randomized controlled trials (RCTs) are currently used to determine the efficacy of a drug, device or treatment protocol under ideal conditions. The goal of Comparative Effectiveness Research and Evidence Based Medicine is to assess an array of treatment options to determine what works best for specific patient groups (e.g. the elderly, racial and ethnic minorities) in clinical situations.

Participants in this program acquire foundational skills and techniques that facilitate critical appraisal of existing multidisciplinary research literature, identify gaps, and then synthesize and evaluate more effective interventions.

Courses within this certificate program carry full graduate course credit at University of California, Irvine’s School of Medicine and most can be directly applied to the school’s MS degree in Biomedical and Translational Sciences (MS-BATS) with departmental approval. Enrollment in these courses is managed via Concurrent Enrollment through UCI Division of Continuing Education.

Who Should Enroll

The Comparative Effectiveness Research and Evidence Based Medicine certificate is ideal for practicing physicians, junior faculty in clinical departments, residents, fellows, 4th year medical students, and others who are interested in the conduct, interpretation and implementation of comparative effectiveness and evidence-based research to improve health care outcomes and the efficiency of medical care.

Career Insight

Occupational summary for medical and clinical laboratory technologists and technicians.

Projected Growth
Annual Salary
(25th-75th Percentile)

Program Benefits

  • Define and conduct new studies that generate evidence to support outcomes-based evaluation of treatment regimens
  • Utilize medical statistics, data analysis, data repositories, linear regressions, survival analysis, meta-analysis, and instrumental variable techniques to access effectiveness of medical interventions
  • Develop the skills required to lead multidisciplinary research teams
  • Develop competency in study design, reflecting the breadth and complexity of comparative effectiveness
  • Identify gaps between research and current clinical practices

Course Schedule

The schedule for these courses is available at the UCI websoc website. Search for courses in the BATS department (Biomedical and Translational Science) and a list of courses in the department will be populated. If the schedule for a course is unavailable, please check again at a later date as the websoc site is updated by the graduate department.

Required Courses

  to be scheduled    
BATS 247
BATS 247
to be scheduled      
BATS 253
BATS 253
      to be scheduled
BATS 251
BATS 251
  to be scheduled    

Course schedules are subject to change. Individual courses may be taken without enrolling in the full certificate.

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Certificate Eligibility and Requirements

Learn How To Earn Your Certificate A Certificate is awarded upon completion of the four (4) required courses, 16 units (160 hours), with a grade of “B” or higher in each course. Students may enter the program at any time, however Introduction to Clinical Medical Statistics or the equivalent is a prerequisite for Comparative Effectiveness Research I & II and Measurement Science, Outcomes Research & Advanced Methods.

To become an official candidate in the program, students pursuing the certificate must submit a Declaration of Candidacy with a non-refundable $125 application fee. Students are encouraged to declare candidacy as soon as possible, but no later than after the third course in the program. To receive the certificate after completing all program requirements, students must submit a Request for Certificate. All requirements must be completed within five (5) years after the student enrolls in his/her first course. Students not pursuing a certificate are welcome to take as many individual courses as they wish.

How to Enroll

Students who are not matriculating students in the UCI MS-BATS Degree Program should apply to the UCI Comparative Effectiveness Research and Evidence Based Medicine Certificate Program administrated by UCI Division of Continuing Education via the Concurrent Enrollment program.*

Students should obtain the Concurrent Enrollment Form and complete sections 1, 2, and 5. Once these sections have been completed, submit the form to the UCI Division of Continuing Education Engineering and Science Department via:

Postal Mail
Attn: Jackie Badwah
UCI Division of Continuing Education
P.O. Box 6050
Irvine, CA 92616-6050

Once your completed form is received, you will be contacted by a representative from UCI Division of Continuing Education. Completed forms are not accepted via email, please submit via postal mail. Please submit original forms only (photocopies will not be accepted).


Dates & Deadlines

The following are the enrollment start & end dates for each quarter:

Spring 2019
Enrollment period for new students: *2/25/19 – 3/15/19
Enrollment deadline for returning students: 3/22/19
Courses begin the week of April 1, 2019

Summer 2019
Enrollment period for new students: 5/6/19 – 5/31/19*
Enrollment deadline for returning students: 6/7/19
Courses begin the week of June 24, 2019

*Note to new students: Enrollment forms and supplementary documents will only be accepted during the enrollment periods for each quarter.

Advisory Committee

  • Ralph V. Clayman, M.D., Professor, Department of Urology, University of California, Irvine School of Medicine
  • Paul Curry, M.D., Past Chief of Staff, Hoag Memorial Hospital Presbyterian; Assistant Professor, Department of Anesthesiology and Perioperative Medicine, University of California, Los Angeles
  • Alan Goldin, M.D., Ph.D., Professor, Microbiology & Molecular Genetics, Department of Anatomy and Neurobiology, University of California, Irvine School of Medicine
  • Sheldon Greenfield, M.D., Donald Bren Professor of Medicine, Executive Director, Center for Health Policy Research, University of California, Irvine School of Medicine
  • Zeev Kain, M.D., Professor and Chair/Associate Dean for Clinical Operations, Department of Anesthesiology & Perioperative Care, University of California, Irvine School of Medicine
  • Sherrie H. Kaplan, Ph.D., MPH, Professor of Medicine, Assistant Vice Chancellor, Healthcare Evaluation and Measurement, Executive Co-Director, Health Policy Research Institute, University of California, Irvine School of Medicine
  • Scott Whitcup, M.D., Executive Vice President, Head R & D & Chief Scientific Officer, Allergan

On-site Training Available

Our Corporate Training specialists can deliver this program or customize one that fits your organization’s specific needs. Visit Corporate Training or call (949) 824-1847 for information.

English Proficiency Requirement
All certificate programs at UCI Division of Continuing Education (classroom and online formats) require professional-level English language proficiency in listening and note-taking, reading comprehension and vocabulary, written expression, and oral presentation.